Return of the Dire Wolf

Relying on deft genetic engineering and ancient, preserved DNA, Colossal scientists deciphered the dire wolf genome, rewrote the genetic code of the common gray wolf to match it, and, using domestic dogs as surrogate mothers, brought Romulus, Remus, and their sister, 2-month-old Khaleesi, into the world during three separate births last fall and this winter—effectively for the first time de-extincting a line of beasts whose live gene pool long ago vanished.

From this interesting cover story in Time about how Colossal has de-extincted The Dire Wolf.

The NYtimes also did a piece.

(Of course, they haven't really recreated the Dire Wolf. Sill interesting.)

In somewhat unrelated news, I've been reading Magic Pill, a book about Ozempic and other GLP-1 drugs. There's a little bit of trivia that I found fascinating. When the scientists were stumped because they couldn't get the GLP-1 in the drug to last more than a few hours after injection, they discovered that the Monitor Lizard's GLP-1 could sustain... but they couldn't get their hands on a Monitor Lizard as there's no legal market for them. One of the scientists managed to convince a rogue zookeeper to sell him one for $250. ("You understand I'm going to euthanize this animal, right?" "Do you have the $250 or not?") Without that illegal transaction, there might not have been any Ozempic.

People who lack the empathy to care about animals at all — I encountered many when I was a vegetarian — I've often been surprised that their selfishness does not translate to "maybe we shouldn't let them go extinct because we can use them!"


John Lithgow Reads Timothy Snyder

Yale professor Timothy Snyder announced this week that he and his wife Marci Shore (also a Yale prof) are leaving America and moving to Canada to teach at the University of Toronto. This is significant because Snyder is an expert on tyranny. His book On Tyranny: 20 Lessons from the Twentieth Century is a succinct and vital read on the subject. It was one of the best books I read while living in Vanuatu during Trump's first term. I highly recommend it.

The first "rule," Do Not Obey In Advance, is being broken by countless individuals and corporations under Trump's second term. Once you're aware of this pithy statement, you'll start to see it happening everywhere, and it's frightening.

Here's John Lithgow reading from the book:


Tim Ferris Talks with Craig Mod

I've mentioned Craig Mod and his books and walking before and over the last couple days have been enjoying his two lengthy conversations with Tim Ferris. Craig is an American who’s been living in Japan for ages, writing and publishing — creating his own books to his own high standards, and living a life dedicated to his art.

When he goes on his lengthy walks (1000s of kilometres so far), he walks for 8 hours a day, stopping to talk to locals, have lunch, take photos, and understand where he is and where he’s going, and then he writes 4 hours per day. He’ll do this every day for his weeks- / month-long journeys. He does this by paring down his device use with Freedom and understanding Sister Corita’s 7th rule: The only rule is work. (I’m putting words in his mouth here.)

You can find the podcast in the usual places by searching for the Tim Ferris Show and then looking for Craig Mod, or you can stream them via YouTube:

Part One

Part Two


Hours of Funk from Around the World

Habibi Funk has released seven free funk mixes. Stream them below or download to your own device.


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